{"product_id":"abm222195","title":"Recombinant Human GH protein","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eGrowth hormone (GH), also known as somatotropin, is a member of a family of growth factors that includes prolactin, placental lactogens, proliferins, and somatolactin. It is a peptide hormone that stimulates growth, cell reproduction and regeneration in humans and other animals. Growth hormone is a 191-amino acid, single-chain polypeptide that is synthesized, stored, and secreted by somatotropic cells within the lateral wings of the anterior pituitary gland. The pulsatile release of GH into circulation is regulated by the concerted actions of the hypothalamic hormones-GH-releasing hormone (GHRH) and somatostatin (SST) as well as by signals from the periphery-ghrelin and leptin. The human GH cDNA encodes a 217 amino acid (a.a.) residue precursor protein with a 26 a.a. putative signal peptide. By alternative splicing, at least four isoforms of GH have been identified.\u003c\/p\u003e\u003cdl\u003e\n\u003cdt\u003eExpression system\u003c\/dt\u003e\n\u003cdd\u003eEscherichia coli.\u003c\/dd\u003e\n\u003cdt\u003ePurity\u003c\/dt\u003e\n\u003cdd\u003e\u0026gt; 98 % by SDS-PAGE and HPLC analyses.\u003c\/dd\u003e\n\u003cdt\u003eMolecular weight\u003c\/dt\u003e\n\u003cdd\u003eApproximately 22 kDa, a single non-glycosylated polypeptide chain containing 191 amino acids\u003c\/dd\u003e\n\u003cdt\u003eEndotoxin\u003c\/dt\u003e\n\u003cdd\u003eLess than 1EU\/μg of rHuGH as determined by LAL method.\u003c\/dd\u003e\n\u003cdt\u003eForm\u003c\/dt\u003e\n\u003cdd\u003eSterile Filtered White lyophilized (freeze-dried) powder. Formulation Lyophilized from a 0.2 μm filtered concentrated solution with 5mM NaHCO3, pH 7.0.\u003c\/dd\u003e\n\u003c\/dl\u003e\u003cp\u003e\u003cem\u003ePackaging image shown for reference. Select a size from the available options.\u003c\/em\u003e\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"100 ug","offer_id":57661932208468,"sku":"ABM222195","price":230.0,"currency_code":"GBP","in_stock":true},{"title":"20 ug","offer_id":57661932241236,"sku":"ABM222196","price":226.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-0fd1f6372ffcfb473d60291b19ad3a3c1ba873bf34f64149b8c025ca5826680b.jpg?v=1792159240","url":"https:\/\/www.abmium.com\/products\/abm222195","provider":"ABMIUM","version":"1.0","type":"link"}