{"product_id":"abm219588","title":"Recombinant Mouse IL-22 protein","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eIL-22 is belonging to IL-10 family of regulatory cytokines which includes IL-10, IL-19, IL-20, IL-22, IL-24 and IL-26. Members of this family share partial homology in their amino acid sequences, but they are dissimilar in their biological functions. Produced by T lymphocytes and dendritic cells, IL-10 contributes to the inflammatory response in vivo. IL-22 signals through CRF2-4 and IL-22. It along with IL-17 is rapidly produced by splenic LTi-like cells and can be also produced by Th17 cells and likely plays a role in the coordinated response of both adaptive and innate immune systems. Recombinant mouse interleukin-22 contains 147 amino acids and it has approximately 81 % and 92 % amino acid sequence identity with human and rat IL-22.\u003c\/p\u003e\u003cdl\u003e\n\u003cdt\u003eExpression system\u003c\/dt\u003e\n\u003cdd\u003eEscherichia coli.\u003c\/dd\u003e\n\u003cdt\u003ePurity\u003c\/dt\u003e\n\u003cdd\u003e\u0026gt; 96 % by SDS-PAGE and HPLC analyses.\u003c\/dd\u003e\n\u003cdt\u003eMolecular weight\u003c\/dt\u003e\n\u003cdd\u003eApproximately 16.6 kDa, a single non-glycosylated polypeptide chain containing 146 amino acids.\u003c\/dd\u003e\n\u003cdt\u003eEndotoxin\u003c\/dt\u003e\n\u003cdd\u003eLess than 1 EU\/μg of rMuIL-22 as determined by LAL method.\u003c\/dd\u003e\n\u003cdt\u003eForm\u003c\/dt\u003e\n\u003cdd\u003eSterile Filtered White lyophilized (freeze-dried) powder. Formulation Lyophilized from a 0.2 μm filtered concentrated solution in 1 × PBS, pH 7.4.\u003c\/dd\u003e\n\u003c\/dl\u003e\u003cp\u003e\u003cem\u003ePackaging image shown for reference. Select a size from the available options.\u003c\/em\u003e\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"10 ug","offer_id":57661820830036,"sku":"ABM219588","price":262.0,"currency_code":"GBP","in_stock":true},{"title":"2 ug","offer_id":57661820862804,"sku":"ABM219589","price":113.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-0fd1f6372ffcfb473d60291b19ad3a3c1ba873bf34f64149b8c025ca5826680b.jpg?v=1792159240","url":"https:\/\/www.abmium.com\/products\/abm219588","provider":"ABMIUM","version":"1.0","type":"link"}