{"product_id":"abm217084","title":"Human Multidrug Resistance-associated Protein 1, ABCC1 ELISA Kit","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eMediates export of organic anions and drugs from the cytoplasm (PubMed: 7961706, PubMed: 16230346, PubMed: 9281595, PubMed: 10064732, PubMed: 11114332). Mediates ATP-dependent transport of glutathione and glutathione conjugates, leukotriene C4, estradiol-17-beta-o-glucuronide, methotrexate, antiviral drugs and other xenobiotics (PubMed: 7961706, PubMed: 16230346, PubMed: 9281595, PubMed: 10064732, PubMed: 11114332). Confers resistance to anticancer drugs by decreasing accumulation of drug in cells, and by mediating ATP- and GSH-dependent drug export (PubMed: 9281595). Hydrolyzes ATP with low efficiency (PubMed: 16230346). Catalyzes the export of sphingosine 1-phosphate from mast cells independently of their degranulation (PubMed: 17050692). Participates in inflammatory response by allowing export of leukotriene C4 from leukotriene C4-synthezing cells (By similarity).\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"48T","offer_id":57661728260436,"sku":"ABM217084","price":205.0,"currency_code":"GBP","in_stock":true},{"title":"96T","offer_id":57661728293204,"sku":"ABM217085","price":293.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-051c4cc74643918baca9c1e7d9bd80649d464d1a71d8b9498bead9c60b2eb9e9.jpg?v=1792159213","url":"https:\/\/www.abmium.com\/products\/abm217084","provider":"ABMIUM","version":"1.0","type":"link"}