{"product_id":"abm215700","title":"Human Nitric Oxide Synthase, Inducible, INOS-NOS2 ELISA Kit","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eProduces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body (PubMed: 7531687, PubMed: 7544004). In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such PTGS2\/COX2 (By similarity). As component of the iNOS-S100A8\/9 transnitrosylase complex involved in the selective inflammatory stimulus-dependent S-nitrosylation of GAPDH on 'Cys-247' implicated in regulation of the GAIT complex activity and probably multiple targets including ANXA5, EZR, MSN and VIM (PubMed: 25417112). Involved in inflammation, enhances the synthesis of proinflammatory mediators such as IL6 and IL8 (PubMed: 19688109).\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"48T","offer_id":57661668000084,"sku":"ABM215700","price":205.0,"currency_code":"GBP","in_stock":true},{"title":"96T","offer_id":57661668032852,"sku":"ABM215701","price":293.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-61bf0ed1af8454d338f473eab75a59348239b710b7d4103101f3b7e8a8e48669.jpg?v=1792159213","url":"https:\/\/www.abmium.com\/products\/abm215700","provider":"ABMIUM","version":"1.0","type":"link"}