{"product_id":"abm215110","title":"Human Vitamin D 25-hydroxylase, CYP2R1 ELISA Kit","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eA cytochrome P450 monooxygenase involved in activation of vitamin D precursors. Catalyzes hydroxylation at C-25 of both forms of vitamin D, vitamin D(2) and D(3) (calciol) (PubMed: 12867411, PubMed: 15465040, PubMed: 18511070). Can metabolize vitamin D analogs\/prodrugs 1alpha-hydroxyvitamin D(2) (doxercalciferol) and 1alpha-hydroxyvitamin D(3) (alfacalcidol) forming 25-hydroxy derivatives (PubMed: 15465040, PubMed: 18511070). Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase) (PubMed: 12867411, PubMed: 15465040, PubMed: 18511070).\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"48T","offer_id":57661709287764,"sku":"ABM215110","price":205.0,"currency_code":"GBP","in_stock":true},{"title":"96T","offer_id":57661709320532,"sku":"ABM215111","price":293.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-9cdb185a9940b588828533db715607819a102fecd8bee7ac203a8d91d5d6c0f8.jpg?v=1792159227","url":"https:\/\/www.abmium.com\/products\/abm215110","provider":"ABMIUM","version":"1.0","type":"link"}