{"product_id":"abm214518","title":"Human Formin-binding Protein 1, FNBP1 ELISA Kit","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eMay act as a link between RND2 signaling and regulation of the actin cytoskeleton (By similarity). Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during the late stage of clathrin-mediated endocytosis. Binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules. Also enhances actin polymerization via the recruitment of WASL\/N-WASP, which in turn activates the Arp2\/3 complex. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. May be required for the lysosomal retention of FASLG\/FASL.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"48T","offer_id":57661744480596,"sku":"ABM214518","price":205.0,"currency_code":"GBP","in_stock":true},{"title":"96T","offer_id":57661744513364,"sku":"ABM214519","price":293.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-e823e67a9299eb532c0f826b80ca52c2a24718c3b6f5c3b6c91c654b9ff86dbf.jpg?v=1792159233","url":"https:\/\/www.abmium.com\/products\/abm214518","provider":"ABMIUM","version":"1.0","type":"link"}