{"product_id":"abm212076","title":"Bovine Acyl-CoA Desaturase, SCD ELISA Kit","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eInvolved in the biosynthesis of highly unsaturated fatty acids (HUFA) from the essential polyunsaturated fatty acids (PUFA) linoleic acid (LA) (18:2n-6) and alpha-linolenic acid (ALA) (18:3n-3) precursors, acting as a fatty acyl-coenzyme A (CoA) desaturase that introduces a cis double bond at carbon 6 of the fatty acyl chain. Catalyzes the first and rate limiting step in this pathway which is the desaturation of LA (18:2n-6) and ALA (18:3n-3) into gamma-linoleate (GLA) (18:3n-6) and stearidonate (18:4n-3), respectively (By similarity). Subsequently, in the biosynthetic pathway of HUFA n-3 series, it desaturates tetracosapentaenoate (24:5n-3) to tetracosahexaenoate (24:6n-3), which is then converted to docosahexaenoate (DHA)(22:6n-3), an important lipid for nervous system function (By similarity). It can also desaturate (11E)-octadecenoate (trans-vaccenoate, a metabolite in the biohydrogenation pathway of LA and the predominant trans fatty acid in cow milk) at carbon 6 generating (6Z,11E)-octadecadienoate (By similarity). In addition to Delta-6 activity, this enzyme exhibits Delta-8 activity with slight biases toward n-3 fatty acyl-CoA substrates (By similarity).\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"48T","offer_id":57661801431380,"sku":"ABM212076","price":205.0,"currency_code":"GBP","in_stock":true},{"title":"96T","offer_id":57661801464148,"sku":"ABM212077","price":293.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-b8509770767a2ec4da22b2c859a4995b1571d7b95478713939fe5d3308406d6a.jpg?v=1792159203","url":"https:\/\/www.abmium.com\/products\/abm212076","provider":"ABMIUM","version":"1.0","type":"link"}