{"product_id":"abm211222","title":"Mouse Catestatin ELISA Kit","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eStrongly inhibits glucose induced insulin release from the pancreas. Inhibits catecholamine release from chromaffin cells and noradrenergic neurons by acting as a non-competitive nicotinic cholinergic antagonist. Can induce mast cell migration, degranulation and production of cytokines and chemokines. Regulates granule biogenesis in endocrine cells by up-regulating the transcription of protease nexin 1 (SERPINE2) via a cAMP-PKA-SP1 pathway. This leads to inhibition of granule protein degradation in the Golgi complex which in turn promotes granule formation (PubMed:21436258). Pyroglutaminated (pGlu)-serpinin exerts an antiapoptotic effect on cells exposed to oxidative stress (PubMed:21537909).\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"48T","offer_id":57661718102356,"sku":"ABM211222","price":205.0,"currency_code":"GBP","in_stock":true},{"title":"96T","offer_id":57661718135124,"sku":"ABM211223","price":293.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-cc47edd43c847cd0f3c9190af914665c4fe11785f90a046669e79ef0acd76f9d.jpg?v=1792159239","url":"https:\/\/www.abmium.com\/products\/abm211222","provider":"ABMIUM","version":"1.0","type":"link"}