{"product_id":"abm207522","title":"Rat Mothers Against Decapentaplegic Homolog 7, SMAD7 ELISA Kit","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eAntagonist of signaling by TGF-beta (transforming growth factor) type 1 receptor superfamily members; has been shown to inhibit TGF-beta (Transforming growth factor) and activin signaling by associating with their receptors thus preventing SMAD2 access. Functions as an adapter to recruit SMURF2 to the TGF-beta receptor complex. Also acts by recruiting the PPP1R15A-PP1 complex to TGFBR1, which promotes its dephosphorylation. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"48T","offer_id":57661167042900,"sku":"ABM207522","price":205.0,"currency_code":"GBP","in_stock":true},{"title":"96T","offer_id":57661167075668,"sku":"ABM207523","price":293.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-e0792440bf721fed5a186c00f0ff3492077cb76c7d561c8e07028c0ae3f38c21.jpg?v=1792159089","url":"https:\/\/www.abmium.com\/products\/abm207522","provider":"ABMIUM","version":"1.0","type":"link"}