{"product_id":"abm207450","title":"Human Interleukin 21, IL-21 ELISA Kit","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eCytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells (By similarity). Implicated in the generation and maintenance of T follicular helper (Tfh) cells and the formation of germinal-centers. Together with IL6, control the early generation of Tfh cells and are critical for an effective antibody response to acute viral infection (By similarity). May play a role in proliferation and maturation of natural killer (NK) cells in synergy with IL15. May regulate proliferation of mature B- and T-cells in response to activating stimuli. In synergy with IL15 and IL18 stimulates interferon gamma production in T-cells and NK cells (PubMed: 11081504, PubMed: 15178704). During T-cell mediated immune response may inhibit dendritic cells (DC) activation and maturation (By similarity).\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"96T","offer_id":57661099245908,"sku":"ABM207450","price":293.0,"currency_code":"GBP","in_stock":true},{"title":"48T","offer_id":57661099278676,"sku":"ABM207451","price":205.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-fa2506bbef5a2bc2b0afd6072da432acf7d91461342df8327ee042c3cab58fe0.jpg?v=1792159083","url":"https:\/\/www.abmium.com\/products\/abm207450","provider":"ABMIUM","version":"1.0","type":"link"}