{"product_id":"abm207330","title":"Human Growth Differentiation Factor 15, GDF15 ELISA Kit","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eRegulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses (PubMed: 28953886, PubMed: 28846097, PubMed: 28846098, PubMed: 28846099, PubMed: 23468844, PubMed: 29046435). Binds to its receptor, GFRAL, and activates GFRAL-expressing neurons localized in the area postrema and nucleus tractus solitarius of the brainstem (PubMed: 28953886, PubMed: 28846097, PubMed: 28846098, PubMed: 28846099). It then triggers the activation of neurons localized within the parabrachial nucleus and central amygdala, which contitutes part of the 'emergency circuit' that shapes feeding responses to stressful conditions (PubMed: 28953886). On hepatocytes, inhibits growth hormone signaling (By similarity).\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"96T","offer_id":57660981870932,"sku":"ABM207330","price":293.0,"currency_code":"GBP","in_stock":true},{"title":"48T","offer_id":57660981903700,"sku":"ABM207331","price":205.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-b32815bcc17920cb1c8ae7a0035ab96c139d739eb9d18204af311a0803571de2.jpg?v=1792159075","url":"https:\/\/www.abmium.com\/products\/abm207330","provider":"ABMIUM","version":"1.0","type":"link"}