{"product_id":"abm204891","title":"PLAU Monoclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eThis gene encodes a secreted serine protease that converts plasminogen to plasmin. The encoded preproprotein is proteolytically processed to generate A and B polypeptide chains. These chains associate via a single disulfide bond to form the catalytically inactive high molecular weight urokinase-type plasminogen activator (HMW-uPA). HMW-uPA can be further processed into the catalytically active low molecular weight urokinase-type plasminogen activator (LMW-uPA). This low molecular weight form does not bind to the urokinase-type plasminogen activator receptor. Mutations in this gene may be associated with Quebec platelet disorder and late-onset Alzheimer's disease. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"100μL","offer_id":57661090627924,"sku":"ABM204891","price":205.0,"currency_code":"GBP","in_stock":true},{"title":"50μL","offer_id":57661090660692,"sku":"ABM204892","price":141.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-87b6aa3d8099acd244fa90eff897f2d1cc5abf7424920989568ae5ebde6f6b1a.jpg?v=1792159090","url":"https:\/\/www.abmium.com\/products\/abm204891","provider":"ABMIUM","version":"1.0","type":"link"}