{"product_id":"abm202463","title":"HLA-F Monoclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eThis gene belongs to the HLA class I heavy chain paralogues. It encodes a non-classical heavy chain that forms a heterodimer with a beta-2 microglobulin light chain, with the heavy chain anchored in the membrane. Unlike most other HLA heavy chains, this molecule is localized in the endoplasmic reticulum and Golgi apparatus, with a small amount present at the cell surface in some cell types. It contains a divergent peptide-binding groove, and is thought to bind a restricted subset of peptides for immune presentation. This gene exhibits few polymorphisms. Multiple transcript variants encoding different isoforms have been found for this gene. These variants lack a coding exon found in transcripts from other HLA paralogues due to an altered splice acceptor site, resulting in a shorter cytoplasmic domain.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"100μL","offer_id":57661155770708,"sku":"ABM202463","price":205.0,"currency_code":"GBP","in_stock":true},{"title":"50μL","offer_id":57661155803476,"sku":"ABM202464","price":141.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-7903132fda5fde0621d9547683c6cd3beb696b0188e91191dc4838babb9f93f9.jpg?v=1792159120","url":"https:\/\/www.abmium.com\/products\/abm202463","provider":"ABMIUM","version":"1.0","type":"link"}