{"product_id":"abm202117","title":"ZAP70 Monoclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eZAP70 (zeta-chain associated protein kinase), a 70 kDa member of the SYK tyrosine kinase family, plays a central role in lymphocyte activation and development, and is implicated in several immune disorders. ZAP70 controls TCR(T-cell antigen receptor)-linked signal transduction pathways. Its key role in thymocytes development and mature T lymphocytes activation has been illustrated by the characterization of several human immunodeficiencies presenting with mutations in the ZAP70 gene. ZAP70 is also expressed in several types of B-cell neoplasm and is easily detected by immunohistochemistry, providing a useful prognostic marker in patients with chronic lymphocytic leukaemia.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"100μL","offer_id":57660781658452,"sku":"ABM202117","price":205.0,"currency_code":"GBP","in_stock":true},{"title":"50μL","offer_id":57660781691220,"sku":"ABM202118","price":141.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-ae54fb1e60dfe3ba080bd7d69eed87586ddb84ff323a6029a434df9e0b0f9b39.jpg?v=1792159115","url":"https:\/\/www.abmium.com\/products\/abm202117","provider":"ABMIUM","version":"1.0","type":"link"}