{"product_id":"abm201843","title":"ABCG2 Monoclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eThe membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR\/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue.Tissue specificity: Highly expressed in placenta. Low expression in small intestine, liver and colon.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"100μL","offer_id":57661514154324,"sku":"ABM201843","price":205.0,"currency_code":"GBP","in_stock":true},{"title":"50μL","offer_id":57661514187092,"sku":"ABM201844","price":141.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-e1310b1f0cc0045cb476b920430b0e0adea4f86360094f3b71a2182190076f72.jpg?v=1792159121","url":"https:\/\/www.abmium.com\/products\/abm201843","provider":"ABMIUM","version":"1.0","type":"link"}