{"product_id":"abm198939","title":"Bcl-10 Monoclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eThis gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. The protein encoded by this gene contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. This protein is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and this protein are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy. Alternative splicing results in multiple transcript variants.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"50ul","offer_id":57661041017172,"sku":"ABM198939","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"100ul","offer_id":57661041049940,"sku":"ABM198940","price":192.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-31c30eae519b0f6da181e1a509702e1ed9fb2cbd7520cf403e6946f861fd1b1e.jpg?v=1792159015","url":"https:\/\/www.abmium.com\/products\/abm198939","provider":"ABMIUM","version":"1.0","type":"link"}