{"product_id":"abm190298","title":"PHC3 Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eComponent of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,Contains 1 FCS-type zinc finger.,Contains 1 SAM (sterile alpha motif) domain.,subunit:Component of chromatin-associated class II polycomb repressive complex 1 (PRC1\/hPRC-H) at least composed of PCGF2\/RNF110, BMI1\/PCGF4, CBX2\/M33, CBX4\/PC2, CBX8\/PC3, PHC1, PHC2, PHC3, SCMH1, RING1 and RNF2\/RING2.,\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"100ul","offer_id":57660783722836,"sku":"ABM190298","price":176.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57660783755604,"sku":"ABM190299","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"20ul","offer_id":57660783788372,"sku":"ABM190300","price":69.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-1ea4c7287cbfdf5088445786c5a5187a69f59f2a2d1db38ede993084a9fd9773.jpg?v=1792241051","url":"https:\/\/www.abmium.com\/products\/abm190298","provider":"ABMIUM","version":"1.0","type":"link"}