{"product_id":"abm190187","title":"TAP2 Rabbit Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eThe membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1| MDR\/TAP| MRP| ALD| OABP| GCN20| White). This protein is a member of the MDR\/TAP subfamily. Members of the MDR\/TAP subfamily are involved in multidrug resistance. This gene is located 7 kb telomeric to gene family member ABCB2. The protein encoded by this gene is involved in antigen presentation. This protein forms a heterodimer with ABCB2 in order to transport peptides from the cytoplasm to the endoplasmic reticulum. Mutations in this gene may be associated with ankylosing spondylitis| insulin-dependent diabetes mellitus| and celiac disease. Alternative splicing of this gene produces products which differ in peptide selectivity and level of restoration of surface expression of MHC class I molecules.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"20ul","offer_id":57661514285396,"sku":"ABM190187","price":69.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57661514318164,"sku":"ABM190188","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"100ul","offer_id":57661514350932,"sku":"ABM190189","price":176.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-536a0f97bdce077c1421613326444b69d0c23eeb567e058a2ad991ca7329494e.jpg?v=1792159024","url":"https:\/\/www.abmium.com\/products\/abm190187","provider":"ABMIUM","version":"1.0","type":"link"}