{"product_id":"abm187946","title":"PSB10 Rabbit Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eThe proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP\/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome| the immunoproteasome| is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family| also known as the T1B family| that is a 20S core beta subunit. Proteolytic processing is required to generate a mature subunit. Expression of this gene is induced by gamma interferon| and this gene product replaces catalytic subunit 2 (proteasome beta 7 subunit) in the immunoproteasome.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"20ul","offer_id":57660811149652,"sku":"ABM187946","price":69.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57660811182420,"sku":"ABM187947","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"100ul","offer_id":57660811215188,"sku":"ABM187948","price":176.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-e9fe71492bf8a9cbca37a7e7c24a78c9f7742fe3b2edd49fbcfee08dff9962ee.jpg?v=1792159023","url":"https:\/\/www.abmium.com\/products\/abm187946","provider":"ABMIUM","version":"1.0","type":"link"}