{"product_id":"abm186860","title":"PCDGE Rabbit Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eThis gene is a member of the protocadherin gamma gene cluster| one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization| suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes| subfamily B contains 7 genes and 2 pseudogenes| and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large| variable region exons are followed by a constant region| containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region| which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"100ul","offer_id":57660842213716,"sku":"ABM186860","price":176.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57660842246484,"sku":"ABM186861","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"20ul","offer_id":57660842279252,"sku":"ABM186862","price":69.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-66ed8e9ad57082d83a6d46329128cf75789148fe463effad380f8df93b783325.jpg?v=1792158978","url":"https:\/\/www.abmium.com\/products\/abm186860","provider":"ABMIUM","version":"1.0","type":"link"}