{"product_id":"abm186857","title":"PCDGD Rabbit Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eThis gene is a member of the protocadherin gamma gene cluster| one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization| suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes| subfamily B contains 7 genes and 2 pseudogenes| and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large| variable region exons are followed by a constant region| containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region| which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"100ul","offer_id":57660840837460,"sku":"ABM186857","price":176.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57660840870228,"sku":"ABM186858","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"20ul","offer_id":57660840902996,"sku":"ABM186859","price":69.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-529698255b852e2a5f0118bde3fc13b5828669bc7f0e4fecbe430604ac570da4.jpg?v=1792158978","url":"https:\/\/www.abmium.com\/products\/abm186857","provider":"ABMIUM","version":"1.0","type":"link"}