{"product_id":"abm184957","title":"MDM2(Phospho Ser186\/S188) Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eThis gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"20ul","offer_id":57661239525716,"sku":"ABM184957","price":69.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57661239558484,"sku":"ABM184958","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"100ul","offer_id":57661239591252,"sku":"ABM184959","price":176.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-8df5c01678db2b466a7db4573df7145e0698366549f70df6eb1ed168dbc1209d.jpg?v=1792159003","url":"https:\/\/www.abmium.com\/products\/abm184957","provider":"ABMIUM","version":"1.0","type":"link"}