{"product_id":"abm177331","title":"Dsg1 Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eThis gene encodes a member of the desmoglein protein subfamily. Desmogleins, along with desmocollins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmoglein family members on chromosome 18. The encoded protein has been identified as a target of auto-antibodies in the autoimmune skin blistering disease pemphigus foliaceus. Disruption of this gene has also been associated with the skin diseases palmoplantar keratoderma and erythroderma.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"20ul","offer_id":57660020916564,"sku":"ABM177331","price":69.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57660020949332,"sku":"ABM177332","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"100ul","offer_id":57660020982100,"sku":"ABM177333","price":176.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-3c9c196c1a341cc3f1d57fdcc4a7453547c9f4d6fe8b45c65a673b953310f8ad.jpg?v=1792158876","url":"https:\/\/www.abmium.com\/products\/abm177331","provider":"ABMIUM","version":"1.0","type":"link"}