{"product_id":"abm177217","title":"IDH3B Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eIsocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses| one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases| which localize to the mitochondrial matrix| and two NADP(+)-dependent isocitrate dehydrogenases| one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits| one beta subunit| and one gamma subunit. The protein encoded by this gene is the beta subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. Multiple alternatively spliced transcript va\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"20ul","offer_id":57659909767508,"sku":"ABM177217","price":69.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57659909800276,"sku":"ABM177218","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"100ul","offer_id":57659909833044,"sku":"ABM177219","price":176.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-1cad39f1a883bbee6c9a2acbaa8b01d4d68fea88d10efe9fadeff20df858802a.jpg?v=1792158866","url":"https:\/\/www.abmium.com\/products\/abm177217","provider":"ABMIUM","version":"1.0","type":"link"}