{"product_id":"abm174364","title":"Rag A\/B Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eHas guanine nucleotide-binding activity but undetectable intrinsic GTPase activity. Required for the amino acid-induced relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. This is a crucial step in the activation of the TOR signaling cascade by amino acids. Involved in the RCC1\/Ran-GTPase pathway. May play a direct role in a TNF-alpha signaling pathway leading to induction of cell death. May alternatively act as a cellular target for adenovirus E3-14. K, an inhibitor of TNF-alpha functions, thereby affecting cell death.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"20ul","offer_id":57660517744980,"sku":"ABM174364","price":69.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57660517777748,"sku":"ABM174365","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"100ul","offer_id":57660517810516,"sku":"ABM174366","price":176.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-cf2443c69fabcd5caf571237394ef491bd525843f7fb825fad5f18ef7040763a.jpg?v=1792158899","url":"https:\/\/www.abmium.com\/products\/abm174364","provider":"ABMIUM","version":"1.0","type":"link"}