{"product_id":"abm172573","title":"PDGFR-Beta Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003ePDGFRB encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. PDGFRB is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses PDGFRB to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"20ul","offer_id":57660054012244,"sku":"ABM172573","price":69.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57660054045012,"sku":"ABM172574","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"100ul","offer_id":57660054077780,"sku":"ABM172575","price":176.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-edb2628528a90ac463696d23b462092030ed20fa17dda3e3e2d95970455ece55.jpg?v=1792158862","url":"https:\/\/www.abmium.com\/products\/abm172573","provider":"ABMIUM","version":"1.0","type":"link"}