{"product_id":"abm169867","title":"ASCC1 Rabbit Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eThis gene encodes a subunit of the activating signal cointegrator 1 (ASC-1) complex. The ASC-1 complex is a transcriptional coactivator that plays an important role in gene transactivation by multiple transcription factors including activating protein 1 (AP-1), nuclear factor kappa-B (NF-kB) and serum response factor (SRF). The encoded protein contains an N-terminal KH-type RNA-binding motif which is required for AP-1 transactivation by the ASC-1 complex. Mutations in this gene are associated with Barrett esophagus and esophageal adenocarcinoma. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"100ul","offer_id":57659765096788,"sku":"ABM169867","price":176.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57659765129556,"sku":"ABM169868","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"20ul","offer_id":57659765162324,"sku":"ABM169869","price":69.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-0516a015ee084e142b176a3a2c822967fbcb71f87085284ff850b8922ea98c4f.jpg?v=1792158892","url":"https:\/\/www.abmium.com\/products\/abm169867","provider":"ABMIUM","version":"1.0","type":"link"}