{"product_id":"abm169783","title":"ACVR1 Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eActivins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins| composed of a ligand-binding extracellular domain with cysteine-rich region| a transmembrane domain| and a cytoplasmic domain with predicted serine\/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding| resulting in phosphorylation of type I receptors by type II receptors. This gene encodes activin A type I receptor which signals a particular\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"100ul","offer_id":57660654190932,"sku":"ABM169783","price":176.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57660654223700,"sku":"ABM169784","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"20ul","offer_id":57660654256468,"sku":"ABM169785","price":69.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-1ea4c7287cbfdf5088445786c5a5187a69f59f2a2d1db38ede993084a9fd9773.jpg?v=1792241051","url":"https:\/\/www.abmium.com\/products\/abm169783","provider":"ABMIUM","version":"1.0","type":"link"}