{"product_id":"abm168307","title":"MRE11 Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eMRE11A encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. MRE11A has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"20ul","offer_id":57660390211924,"sku":"ABM168307","price":69.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57660390244692,"sku":"ABM168308","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"100ul","offer_id":57660390277460,"sku":"ABM168309","price":176.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-5d4f8b9e069888d6150915de0c2e274312d10a1e3dbfc3a85351b6c14df77626.jpg?v=1792158834","url":"https:\/\/www.abmium.com\/products\/abm168307","provider":"ABMIUM","version":"1.0","type":"link"}