{"product_id":"abm167578","title":"MDM2 Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eMDM2 encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. MDM2 is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"20ul","offer_id":57659880440148,"sku":"ABM167578","price":69.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57659880472916,"sku":"ABM167579","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"100ul","offer_id":57659880505684,"sku":"ABM167580","price":176.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-cd634de1b6289f4cbb4fec99338e8ac3f5a53ff336f1fca874544d28b73c3caf.jpg?v=1792158853","url":"https:\/\/www.abmium.com\/products\/abm167578","provider":"ABMIUM","version":"1.0","type":"link"}