{"product_id":"abm162355","title":"GHR Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eGHR encodes a member of the type I cytokine receptor family, which is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature. In humans and rabbits, but not rodents, growth hormone binding protein (GHBP) is generated by proteolytic cleavage of the extracellular ligand-binding domain from the mature growth hormone receptor protein. Multiple alternatively spliced transcript variants have been found for this gene.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"20ul","offer_id":57660539109716,"sku":"ABM162355","price":69.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57660539142484,"sku":"ABM162356","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"100ul","offer_id":57660539175252,"sku":"ABM162357","price":176.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-f85aca87cfcb83d5d07a58859923c49b12ac4ea0aaf21ca5bdc778fe8aad0aab.jpg?v=1792157314","url":"https:\/\/www.abmium.com\/products\/abm162355","provider":"ABMIUM","version":"1.0","type":"link"}