{"product_id":"abm155445","title":"Caveolin-1 Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eThe scaffolding protein (caveolin 1) encoded by CAV1 is the main component of the caveolae plasma membranes found in most cell types. Caveolin 1 links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. CAV1 is a tumor suppressor gene candidate and a negative regulator of the Ras-p42\/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in CAV1 have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"20ul","offer_id":57659755266388,"sku":"ABM155445","price":69.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57659755299156,"sku":"ABM155446","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"100ul","offer_id":57659755331924,"sku":"ABM155447","price":176.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-d58b3a458526c750108df9fa876be96eab246ecfd8c073f2d2abc7be38ce7770.jpg?v=1792157319","url":"https:\/\/www.abmium.com\/products\/abm155445","provider":"ABMIUM","version":"1.0","type":"link"}