{"product_id":"abm155361","title":"NFκB-p100(Phospho Ser869) Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eThis gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, some of which may result in the formation of fusion proteins. There is a pseudogene for this gene on chromosome 18. Alternative splicing results in multiple transcript variants.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"100ul","offer_id":57660533113172,"sku":"ABM155361","price":176.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57660533145940,"sku":"ABM155362","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"20ul","offer_id":57660533178708,"sku":"ABM155363","price":69.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-0b861b5f6e39e954b6b94019cf1bef82fc08c0653837c3367a6b5d93dabe2745.jpg?v=1792157312","url":"https:\/\/www.abmium.com\/products\/abm155361","provider":"ABMIUM","version":"1.0","type":"link"}