ABMIUM target intelligence

CD40LG

CD40 ligand

CD40LG identifies CD40 ligand in Homo sapiens (Human). This target record connects NCBI Gene 959, UniProtKB P29965 and related ABMIUM catalogue products.

Read full target overview
OrganismMultiple species; representative: Homo sapiens (Human) NCBI Gene959 UniProtP29965

ABMIUM research catalogue

Research Products

Loading products for CD40LG…

Alternative names and identifiers

Names used across publications, databases and supplier catalogues.

CD40LCD40 ligandCD154HIGM1IGMIMD3T-BAMTNFSF5TRAPgp39hCD40LLy-62Tnlg8b

Biological function

CD40LG (CD154) is a TNF-superfamily ligand expressed prominently on activated T cells. Binding to CD40 regulates B-cell activation and function and is required for normal immunoglobulin class switching and broader costimulatory immune signalling.

Research context

CD40LG is widely studied in T-cell–B-cell communication, humoral immunity, immunoglobulin class switching, immune activation and inflammatory signalling. Reagent selection should consider species, activation state, sample type, assay format, application and supporting validation.