ABMIUM target intelligence

APOA1

apolipoprotein A1

APOA1 encodes apolipoprotein A1; the mature protein apolipoprotein A-I (ApoA-I) is the major protein component of plasma HDL and a central mediator of cholesterol efflux and reverse cholesterol transport.

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OrganismMultiple species; representative: Homo sapiens (Human) NCBI Gene335 UniProtP02647

ABMIUM research catalogue

Research Products

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Alternative names and identifiers

Names used across publications, databases and supplier catalogues.

Apolipoprotein A-IApoA-IApo-AIAMYLD3HPALP2apo(a)Alp-1Brp-14Ltw-1Lvtw-1Sep-1Sep-2

Biological function

Apolipoprotein A-I promotes export of cellular cholesterol to HDL and transport toward the liver for excretion. ApoA-I also serves as a cofactor for lecithin-cholesterol acyltransferase (LCAT), supporting plasma cholesteryl-ester formation and HDL maturation.

Research context

APOA1 is a core target in HDL assembly, cholesterol efflux, reverse cholesterol transport and broader lipid-metabolism research. Experimental interpretation should distinguish gene or protein abundance from HDL particle composition and follow product-specific species, sample and application validation.