{"product_id":"elk-es9244-elob-rabbit-pab","title":"ELOB rabbit pAb","description":"\u003cp\u003eELOB rabbit pAb is a research-use antibody from ELK Biotechnology for studying ELOB in WB, ELISA workflows with listed reactivity for Human, Mouse, Rat. Specifications and supporting documents below should be reviewed when planning the experiment.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eThis gene encodes the protein elongin B, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A\/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. Pseudogenes have been identified on chromosomes 11 and 13. [provided by RefSeq, Aug 2008],\u003c\/p\u003e\u003ch3\u003eAdditional antibody information\u003c\/h3\u003e\u003ctable\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003eSpecificity\u003c\/th\u003e\n\u003ctd\u003eELOB Polyclonal Antibody detects endogenous levels of protein.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eValidation evidence captions\u003c\/th\u003e\n\u003ctd\u003eWestern blot analysis of lysates from K562 cells, primary antibody was diluted at 1:1000, 4°over night\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e\u003csection data-abmium-seo-guidance=\"true\"\u003e\u003ch2\u003eHow to evaluate ELOB rabbit pAb\u003c\/h2\u003e\n\u003cp\u003eAssess this research-use product against the requirements of your experimental workflow before ordering.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eConfirm the listed species reactivity and experimental application.\u003c\/li\u003e\n\u003cli\u003eReview clonality, host species, format, concentration and storage conditions.\u003c\/li\u003e\n\u003cli\u003eUse lot-specific documentation and suitable positive and negative controls.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eIf a specification or current document is not shown, contact ABMIUM scientific support for assistance before use.\u003c\/p\u003e\u003c\/section\u003e","brand":"ELK Biotechnology","offers":[{"title":"Unconjugated \/ 100µL","offer_id":56187521302868,"sku":"ABM110029","price":220.0,"currency_code":"GBP","in_stock":true},{"title":"Unconjugated \/ 50µL","offer_id":56187521335636,"sku":"ABM100165","price":132.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/ES9244-c-1.jpg?v=1782055960","url":"https:\/\/www.abmium.com\/ja\/products\/elk-es9244-elob-rabbit-pab","provider":"ABMIUM","version":"1.0","type":"link"}