{"product_id":"elk-es3096-p140cap-rabbit-pab","title":"p140Cap rabbit pAb","description":"\u003cp\u003ep140Cap rabbit pAb is a research-use antibody from ELK Biotechnology for studying p140Cap in WB, ELISA workflows with listed reactivity for Human, Mouse, Rat. Specifications and supporting documents below should be reviewed when planning the experiment.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003efunction:Delays the onset of cell spreading in the early stages of cell adhesion to fibronectin. Also involved in calcium-dependent exocytosis from PC12 cells.,PTM:Tyrosine-phosphorylated in response to EGF and to cell adhesion to integrin ligands.,similarity:Belongs to the p140Cap family.,subcellular location:Localized to the perinuclear region, lamellopodia, cortical actin and actin stress fibers but not to focal adhesions.,subunit:Interacts with the N-terminal coiled-coil region of SNAP25 (By similarity). Interacts with BCAR1\/p130Cas through its C-terminal domain.,\u003c\/p\u003e\u003ch3\u003eAdditional antibody information\u003c\/h3\u003e\u003ctable\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003eSpecificity\u003c\/th\u003e\n\u003ctd\u003ep140Cap Polyclonal Antibody detects endogenous levels of p140Cap protein.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eValidation evidence captions\u003c\/th\u003e\n\u003ctd\u003eWestern Blot analysis of various cells using p140Cap Polyclonal Antibody diluted at 1:500 | Western Blot analysis of HeLa cells using p140Cap Polyclonal Antibody diluted at 1:500\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e","brand":"ELK Biotechnology","offers":[{"title":"Unconjugated \/ 100µL","offer_id":56186528465236,"sku":"ABM107399","price":220.0,"currency_code":"GBP","in_stock":true},{"title":"Unconjugated \/ 50µL","offer_id":56186528498004,"sku":"ABM97535","price":132.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/ES3096-c-1.jpg?v=1782045529","url":"https:\/\/www.abmium.com\/ja\/products\/elk-es3096-p140cap-rabbit-pab","provider":"ABMIUM","version":"1.0","type":"link"}