ABMIUM target intelligence

F3

coagulation factor III, tissue factor

Coagulation factor III (F3), better known as tissue factor or CD142, is a membrane glycoprotein that initiates the extrinsic coagulation pathway. ABMIUM catalogue products linked below support research on tissue factor/F3 biology.

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OrganismMultiple species; representative: Homo sapiens (Human) NCBI Gene2152 UniProtP13726

ABMIUM research catalogue

Research Products

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Alternative names and identifiers

Names used across publications, databases and supplier catalogues.

TFTissue factorCD142TFACf-3

Biological function

Coagulation factor III (F3/tissue factor/CD142) is the cellular receptor and cofactor for coagulation factor VII/VIIa. Formation of the tissue factor-factor VIIa complex initiates the extrinsic coagulation cascade and promotes activation of factors IX and X, linking tissue injury to thrombin generation and haemostasis.

Research context

Tissue factor (F3/coagulation factor III/CD142) is commonly studied in coagulation, thrombosis, vascular biology, haemostasis and inflammation-associated tissue-factor signalling. Use the catalogue filters below to review ABMIUM products associated with F3, then confirm species, sample type, assay format, application and product-level validation before use.