ABMIUM target intelligence
beclin 1
BECN1 (beclin 1; Beclin-1/ATG6) is a core autophagy regulator and class III PI3K-complex component linking PI3P production to autophagosome initiation and membrane trafficking.
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Names used across publications, databases and supplier catalogues.
Beclin-1 acts as a core subunit of class III phosphatidylinositol 3-kinase complexes that generate PI3P. Distinct BECN1-containing complexes support autophagosome initiation, autophagosome maturation and endocytic trafficking, making BECN1 central to macroautophagy and membrane-remodelling pathways.
BECN1 is widely studied in autophagy flux, autophagosome biogenesis, vesicle trafficking, nutrient and stress responses, and cell-death regulation. Abmium catalogue products can support BECN1 protein-expression and pathway studies; confirm species, sample type, application and product-level validation before use.