ABMIUM target intelligence
amyloid beta precursor like protein 1
APLP1 (amyloid beta precursor like protein 1; APLP) is a neuronal membrane glycoprotein in the amyloid precursor protein family. It undergoes secretase-dependent processing and is studied in synaptic maturation, neuronal signalling and APP-family biology.
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Names used across publications, databases and supplier catalogues.
APLP1 is processed by secretases in a manner related to other amyloid precursor protein family members. Reviewed UniProt supports roles in postsynaptic function, signalling through C-terminal binding partners and regulation of neurite outgrowth through extracellular-matrix interactions.
APLP1 is studied in neuronal development, synaptic biology, neurite outgrowth and comparative APP-family processing. Its relationship to APP-family signalling makes full-name target identification important when selecting reagents. ABMIUM product links should be checked for application- and species-specific validation.