ABMIUM target intelligence

ACVRL1

activin A receptor like type 1

Activin A receptor like type 1 (ACVRL1), also known as ALK1, is a TGF-beta superfamily type I serine/threonine kinase receptor. This ABMIUM target record links ACVRL1/ALK1 biology with catalogue-backed research products and verified human identifiers.

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OrganismMultiple species; representative: Homo sapiens (Human) NCBI Gene94 UniProtP37023

ABMIUM research catalogue

Research Products

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Alternative names and identifiers

Names used across publications, databases and supplier catalogues.

Activin receptor type-1-likeALK-1ACVL1ACVRLK1HHTHHT2ORW2SKR3TSR-I

Biological function

ACVRL1/ALK1 is a type I receptor for BMP9 (GDF2) and BMP10. Ligand-bound receptor complexes activate receptor serine/threonine kinase signalling and downstream SMAD transcriptional regulators, supporting normal vascular development and endothelial signalling.

Research context

ACVRL1 (ALK1) is studied in TGF-beta/BMP signalling, endothelial biology, angiogenesis and vascular-development research. Use the ABMIUM catalogue links on this page to compare ACVRL1 research products, then confirm species, application and product-level validation for the intended experiment.