{"product_id":"elk-es7822-mnk1-phospho-thr255-rabbit-pab","title":"Mnk1 (phospho Thr255) rabbit pAb","description":"\u003cp\u003eMnk1 (phospho Thr255) rabbit pAb is a research-use antibody from ELK Biotechnology for studying Mnk1 in WB, IHC workflows with listed reactivity for Human, Mouse, Rat. Specifications and supporting documents below should be reviewed when planning the experiment.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eMAP kinase interacting serine\/threonine kinase 1(MKNK1) Homo sapiens This gene encodes a Ser\/Thr protein kinase that interacts with, and is activated by ERK1 and p38 mitogen-activated protein kinases, and thus may play a role in the response to environmental stress and cytokines. This kinase may also regulate transcription by phosphorylating eIF4E via interaction with the C-terminal region of eIF4G. Alternatively spliced transcript variants have been noted for this gene. [provided by RefSeq, Jan 2012],\u003c\/p\u003e\u003ch3\u003eAdditional antibody information\u003c\/h3\u003e\u003ctable\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003eSpecificity\u003c\/th\u003e\n\u003ctd\u003ePhospho-Mnk1 (T255) Polyclonal Antibody detects endogenous levels of Mnk1 protein only when phosphorylated at T255.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eValidation evidence captions\u003c\/th\u003e\n\u003ctd\u003eEnzyme-Linked Immunosorbent Assay (Phospho-ELISA) for Immunogen Phosphopeptide (Phospho-left) and Non-Phosphopeptide (Phospho-right), using MNK1 (Phospho-Thr255) Antibody | Western blot analysis of lysates from HeLa cells treated with Adriamycin 0.5ug\/ml 24h, using MNK1 (Phospho-Thr255) Antibody. The lane on the right is blocked with the phospho peptide. | Immunohistochemical analysis of paraffin-embedded human cervical carcinoma. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e","brand":"ELK Biotechnology","offers":[{"title":"Unconjugated \/ 100µL","offer_id":56187305132372,"sku":"ABM109479","price":220.0,"currency_code":"GBP","in_stock":true},{"title":"Unconjugated \/ 50µL","offer_id":56187305165140,"sku":"ABM99615","price":132.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/ES7822-c-1.jpg?v=1782052092","url":"https:\/\/www.abmium.com\/it\/products\/elk-es7822-mnk1-phospho-thr255-rabbit-pab","provider":"ABMIUM","version":"1.0","type":"link"}