ABMIUM target intelligence

C1QBP

complement C1q binding protein

C1QBP (complement C1q binding protein), also known as p32, gC1qR and HABP1, is a multifunctional protein studied in complement regulation, mitochondrial protein synthesis and RNA-associated cellular processes.

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OrganismMultiple species; representative: Homo sapiens (Human) NCBI Gene708 UniProtQ07021

ABMIUM research catalogue

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Alternative names and identifiers

Names used across publications, databases and supplier catalogues.

Complement component 1 Q subcomponent-binding protein, mitochondrialHABP1COXPD33GC1QBPSF2AP32SF2P32gC1Q-Rp32fa14h03sb:cb785si:ch1073-329n19.2wu:fa14h03zgc:110137

Biological function

C1QBP is a multifunctional, predominantly mitochondrial protein with established roles in mitochondrial ribosome function and protein synthesis. NCBI-curated evidence also describes binding to the globular heads of complement C1q and inhibition of C1 activation. Its p32, gC1qR and HABP1 names reflect experimental contexts reported for the same protein.

Research context

C1QBP is used in research on complement and C1q biology, mitochondrial translation and ribosome function, RNA-associated processes, inflammation and cellular stress. Experimental interpretation should distinguish mitochondrial from cell-surface or other extramitochondrial contexts and account for species, sample type and assay format.