{"product_id":"tribio-total-histone-h3-acetylation-detection-fluorometric","title":"Total Histone H3 Acetylation Detection (Fluorometric) ELISA Kit","description":"\u003cp\u003e\u003cstrong\u003eTotal Histone H3 Acetylation Detection (Fluorometric) ELISA Kit\u003c\/strong\u003e is a research-use solid-phase ELISA for quantitative measurement of Total Histone H3 Acetylation Detection (Fluorometric).\u003c\/p\u003e\n\u003cp\u003eHistone H3 acetylation involves the addition of acetyl groups to lysine residues on histone proteins, which neutralizes their positive charge and relaxes chromatin structure, facilitating gene transcription, which are associated with DNA in chromatin. Histone acetylation is regulated by histone acetyltransferases (HATs), which add acetyl groups, and histone deacetylases (HDACs), which remove them. Histone H3 acetylation is tightly involved in cell cycle regulation, cell proliferation, and apoptosis. Disruption of histone acetylation balance in cancer cells, linked to abnormal transcription factor binding, promotes tumorigenesis, cancer progression, and metastasis\u003c\/p\u003e","brand":"TriBio Science","offers":[{"title":"1x96-well plate","offer_id":57411029270868,"sku":"ABM148418-1","price":627.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/TBS32122-1.jpg?v=1791834067","url":"https:\/\/www.abmium.com\/fr\/products\/tribio-total-histone-h3-acetylation-detection-fluorometric","provider":"ABMIUM","version":"1.0","type":"link"}