{"product_id":"tribio-ml210-gpx4-inhibitor-ferroptosis-inducer","title":"ML210, GPX4 inhibitor; Ferroptosis Inducer","description":"\u003cp\u003eML210 inhibits glutathione peroxidase 4 (GPX4), an important selenoenzyme that protects cells from ferroptosis caused by iron-catalyzed formation of free radicals from lipid peroxides. Exposure of several treatment-resistant cancer cell lines exhibiting a high mesenchymal state to ML210 resulted in selective induction of ferroptosis. ML210 is selectively lethal to HRAS g12v expressing cells (IC 50 = 7.1 nM for BJeLR cells) compared to isogenic cells without HRAS g12v (IC 50 = 272 nM for BJeH-LT cells). LUHMES dopaminergic neurons are highly susceptible to ML210-induced ferroptosis\u003c\/p\u003e","brand":"TriBio Science","offers":[{"title":"10 MG","offer_id":57410938208596,"sku":"ABM147361-1","price":167.0,"currency_code":"USD","in_stock":true},{"title":"50 MG","offer_id":57410938241364,"sku":"ABM147361-2","price":569.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/TBI4002.png?v=1791103993","url":"https:\/\/www.abmium.com\/fr\/products\/tribio-ml210-gpx4-inhibitor-ferroptosis-inducer","provider":"ABMIUM","version":"1.0","type":"link"}