{"product_id":"tribio-importazole-importin-b-mediated-nuclear-import-blocker","title":"Importazole, Importin-b-mediated nuclear import blocker","description":"\u003cp\u003eSpecifically inhibits importin-β-mediated nuclear import without disrupting transportin-mediated nuclear import or CRM1-mediated nuclear export. When added to cells during mitosis it impairs the release of an importin-β cargo probe and causes defects in spindle assembly. Inhibition of importin-β function is most likely mediated by blocking its interaction with RanGTP. It is an important new tool to probe the function of the importin-β\/RanGTP pathway. Cell permeable\u003c\/p\u003e","brand":"TriBio Science","offers":[{"title":"25 MG","offer_id":57410916286804,"sku":"ABM147176-1","price":327.0,"currency_code":"GBP","in_stock":true},{"title":"5 MG","offer_id":57410916319572,"sku":"ABM147176-2","price":82.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/TBI1412.png?v=1791103630","url":"https:\/\/www.abmium.com\/fr\/products\/tribio-importazole-importin-b-mediated-nuclear-import-blocker","provider":"ABMIUM","version":"1.0","type":"link"}