{"product_id":"tribio-gw-2580-cfms-kinase-inhibitor","title":"GW-2580, cFMS kinase inhibitor","description":"\u003cp\u003ePotent and selective inhibitor of cFMS receptor kinase. Completely inhibits cFMS in vitro at 60 nM with no activity against 26 other kinases. Completely inhibits CSF-1 induced growth of mouse M-NFS-60 myeloid cells and human monocytes (at 1 μM). Completely inhibits bone degradation in human osteoclasts, rat calvaria and fetal long bone. Inhibits LPS-induced TNF production in mice. Abrogates infiltration of macrophages into synovial joints of arthritic mice. Active in vivo\u003c\/p\u003e","brand":"TriBio Science","offers":[{"title":"25 MG","offer_id":57410912125268,"sku":"ABM147113-1","price":470.0,"currency_code":"GBP","in_stock":true},{"title":"5 MG","offer_id":57410912158036,"sku":"ABM147113-2","price":118.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/TBI2143.png?v=1791103621","url":"https:\/\/www.abmium.com\/fr\/products\/tribio-gw-2580-cfms-kinase-inhibitor","provider":"ABMIUM","version":"1.0","type":"link"}