{"product_id":"tribio-cgp-37157-mitochondrial-na-ca2-exchanger-inhibitor","title":"CGP-37157, Mitochondrial Na+\/Ca2+ exchanger inhibitor","description":"\u003cp\u003eInhibits the mitochondrial Na + -Ca 2+ exchanger (NCX) in isolated heart mitochondria, IC 50 =0.36 μM. Does not inhibit the plasmalemmal NCX. Also inhibits voltage-gated Ca 2+ channels in intact cells and therefore its use in cellular studies must employ adequate controls. Prevents sudden death in a Guinea pig model of heart failure. Displays pronounced cytoprotective effects in chromaffin cells and in neuronal injury models. Blood-brain barrier permeant\u003c\/p\u003e","brand":"TriBio Science","offers":[{"title":"10 MG","offer_id":57410890203476,"sku":"ABM146810-1","price":131.0,"currency_code":"GBP","in_stock":true},{"title":"50 MG","offer_id":57410890236244,"sku":"ABM146810-2","price":531.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/TBI4250-1.jpg?v=1791103420","url":"https:\/\/www.abmium.com\/fr\/products\/tribio-cgp-37157-mitochondrial-na-ca2-exchanger-inhibitor","provider":"ABMIUM","version":"1.0","type":"link"}