{"product_id":"tribio-cd38-cyclase-activity-assay-kit-fluorometric","title":"CD38 (Cyclase) Activity Assay Kit (Fluorometric)","description":"\u003cp\u003eCD38, also known as ADP-ribosyl cyclase, is a multifunctional ectoenzyme expressed in many immune cells including CD4+, CD8+, B lymphocytes and natural killer cells. It functions in cell adhesion, signal transduction and calcium signaling. CD38 is involved in the metabolism of nicotinamide adenine dinucleotide (NAD+) and nicotinamide adenine dinucleotide phosphate (NADP). The results are the production of Ca2+-mobilizing compounds, such as cyclic ADP ribose (cADPR) and ADP ribose (ADPR). CD38 is used as a marker for poor prognosis in chronic lymphocytic leukemia and multiple myeloma and is an attractive cancer immunotherapy drug target\u003c\/p\u003e\n\u003cp\u003eTribioscience’s CD38 Assay Kit is a simple and fast fluorometric assay that measures the cyclase activity of CD38 in biological samples. CD38 catalyzes the conversion of nicotinamide guanine dinucleotide (NGD+) to cyclic GDP-ribose (cGDPR) which can be measured by fluorometric method at Ex\/Em=300 nm\/410 nm\u003c\/p\u003e","brand":"TriBio Science","offers":[{"title":"100 tests","offer_id":57410992505172,"sku":"ABM147978-1","price":445.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/TBS2100.jpg?v=1791104411","url":"https:\/\/www.abmium.com\/fr\/products\/tribio-cd38-cyclase-activity-assay-kit-fluorometric","provider":"ABMIUM","version":"1.0","type":"link"}