{"product_id":"tribio-ac1903-trpc5-blocker","title":"AC1903, TRPC5 blocker","description":"\u003cp\u003eA potent and selective TRPC5 blocker. Suppresses severe proteinuria and prevents podocyte loss in a transgenic rat model of focal segmental glomerulosclerosis. It also provided therapeutic benefit in a rat model of hypertensive proteineuric kidney disease. The use of this selective tool compound provided a mechanistic rationale for targeting TRPC5 channels in progressive chronic kidney diseases and paves the way for the discovery of new therapeutics. Active in vivo\u003c\/p\u003e","brand":"TriBio Science","offers":[{"title":"10 MG","offer_id":57410862022996,"sku":"ABM146564-1","price":114.0,"currency_code":"GBP","in_stock":true},{"title":"50 MG","offer_id":57410862055764,"sku":"ABM146564-2","price":458.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/TBI3375-1.png?v=1791103223","url":"https:\/\/www.abmium.com\/fr\/products\/tribio-ac1903-trpc5-blocker","provider":"ABMIUM","version":"1.0","type":"link"}